Caribe Tours: Santo Domingo → Santiago
Caribe Tours covers the Santo Domingo → Santiago route with 6 departures a day: the first at 06:00 and the last at 16:00, duration 2 h 15 min. The local fare is around RD$450; with Guagualine you book a seat from $29 USD per person.
Last verified: 2026-07-20 · Caribe Tours
Initial research data. We confirm by phone with the operator before every sale.
Santo Domingo → Santiago bus schedule
| Departure | Operator | Terminal |
|---|---|---|
| 06:00 | Caribe Tours | Caribe Tours Terminal Santo Domingo |
| 08:00 | Caribe Tours | Caribe Tours Terminal Santo Domingo |
| 10:00 | Caribe Tours | Caribe Tours Terminal Santo Domingo |
| 12:00 | Caribe Tours | Caribe Tours Terminal Santo Domingo |
| 14:00 | Caribe Tours | Caribe Tours Terminal Santo Domingo |
| 16:00 48 h cutoff | Caribe Tours | Caribe Tours Terminal Santo Domingo |
Representative departures of a roughly hourly service. Confirm exact times by phone.
The last departure of the day is never sold with a Guagualine booking: if your bus fails there must always be a later departure as plan B.
Local schedules and prices are indicative and can change without notice from the operator. We verify them before confirming every booking.
Guagualine is an independent booking agency. We are not the official website of Caribe Tours and we are not affiliated with this operator. Operator names are used to identify the transport service each one provides.